Chemical composition and evaluation of antibacterial and antioxidant activities of the essential oil of Croton urucurana Baillon (Euphorbiaceae) stem bark

Journal of the Brazilian Chemical Society

Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil¹  Bonani, Vanderléa F. L.¹  Hess, Sônia C.¹  Peruzzo, Gisele M.¹  Peres, Marize T. L. P.¹  Stuker, Caroline Z.¹  Poppi, Nilva Ré¹  Morel, Ademir Farias¹  Simionatto, Euclésio¹  Raposo Júnior, Jorge Luiz¹  Universidade Federal de Santa Maria, Santa Maria, Brazil¹ 

关键词: Croton urucurana;    essential oil;    antioxidant;    DPPH assay;    antimicrobial acticity;   

DOI  :  10.1590/S0103-50532007000500002

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The essential oil obtained from the stem bark of Croton urucurana Baillon (Euphorbiaceae) was analysed by GC and GC-MS. 83 compounds were identified and borneol (14.7%), bornyl acetate (5.2%), 1-isopropyl-7-methyl-4-methylene-1,3,4,5,6,8-hexahydro-2H-naphthalen-4a-ol (14.7%), sesquicineole (10.5%) and g-gurjunene epoxide (5.4%) were the main components. The EC50 value of the crude essential oil in the DPPH free radical scavenging assay was 3.21 mg mL-1. The fraction of the crude essential oil that presented antioxidant activity was purified by prep-TLC on silica gel. GC and GC-MS analysis revealed that a-bisabolol (38.3%), a-eudesmol (9.3%) and guaiol (8.2%) were the main components of the antioxidant fraction. The EC50 value measured for the bioactive oil fraction in the DPPH assay was 1.05 mg mL-1. The antimicrobial activity of the crude essential oil was assayed against seven Gram-positive and Gram-negative bacteria and three yeasts. Measured MIC values ranged from 1.25 to 10.00 mg mL-1.

【 授权许可】

Unknown