Tetraammine ruthenate complexes: cationic SAMs for cytochrome c recognition

Journal of the Brazilian Chemical Society

Solange De Oliveira Pinheiro¹  Francisco O. N. Da Silva¹  Idalina M. M. De Carvalho¹  Luiz G. De França Lopes¹  Marcia L. A. Temperini²  Gustavo F. S. De Andrade²  Ícaro De Sousa Moreira¹  Izaura C. N. Diógenes¹ 

[1] ,Universidade Federal do Ceará Departamento de Química Orgânica e Inorgânica Fortaleza CE ,Brazil

关键词: self-assembled monolayers;    cytochrome c;    tetraamineruthenate complexes;    sulfur ligands;   

DOI  :  10.1590/S0103-50532006000800016

来源: SciELO

【 摘 要 】

The redox process of the cyt c metalloprotein was assessed by the cationic SAMs formed with [Ru(CNPy)(NH3)4(1,4-dt)]2+ and [Ru(CNPy)(NH3)4(pyS)]2+ complexes on gold, where CNPy = 4-cyanopyridine, pyS = 4-mercaptopyridine and 1,4-dt = dithiane. The observed cyt c redox potentials are indicative of the native protein form. The voltammograms, however, were observed to be affected by the conformation of the modifiers, determined by SERS spectroscopy. The [Ru(CNPy)(NH3)4(pyS)]2+ complex, which exhibits trans conformation on the surface, presented a well-defined voltammogram. On the other hand, the gauche conformation of the [Ru(CNPy)(NH3)4(1,4-dt)]2+ SAM seems to make the assessment of the cyt c hET reaction difficult. The reductive desorption potentials, at -0.52 and -0.64 V vs Ag|AgCl|Cl- for the [Ru(CNPy)(NH3)4(1,4-dt)]2+ and [Ru(CNPy)(NH3)4(pyS)]2+ SAMs, respectively, are indicative of the bonding mode with the surface and the pi withdrawing capability of the CNpy ligand.

【 授权许可】

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