期刊论文详细信息
Journal of the Brazilian Chemical Society | |
Flow injection determination of metronidazole through spectrophotometric measurement of the nitrite ion produced upon alkaline hydrolysis | |
Simone S. Simões2  Everaldo P. Medeiros2  Edvaldo N. Gaião2  Wellington S. Lyra2  Pablo N. T. Moreira2  Mario C. U. Araújo2  Edvan C. Silva2  Valberes B. Nascimento1  | |
[1] ,Universidade Federal da Paraíba CCEN Departamento de QuímicaJoão Pessoa PB ,Brazil | |
关键词: flow injection analysis; spectrophotometry; pharmaceuticals; metronidazole; nitrite; | |
DOI : 10.1590/S0103-50532006000300028 | |
来源: SciELO | |
【 摘 要 】
A new method for metronidazole determination, based on spectrometric monitoring of a diazonium salt produced in-line by alkaline hydrolysis released nitrite ions, was developed and successfully applied to pharmaceutical tablets (r = 0.9993, 2.0-20.0 mg L-1, DL = 0.7 mg L-1) with no interference from common ingredients accompanying the drug.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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