期刊论文详细信息
Journal of the Brazilian Chemical Society | |
Flow injection determination of metronidazole through spectrophotometric measurement of the nitrite ion produced upon alkaline hydrolysis | |
Lyra, Wellington S.1  Araújo, Mario C. U.1  Silva, Edvan C.1  Nascimento, Valberes B.1  Universidade Federal Rural de Pernambuco, Recife, Brazil1  Gaião, Edvaldo N.1  Moreira, Pablo N. T.1  Simões, Simone S.1  Medeiros, Everaldo P.1  Universidade Federal da Paraíba, João Pessoa, Brazil1  | |
关键词: flow injection analysis; spectrophotometry; pharmaceuticals; metronidazole; nitrite; | |
DOI : 10.1590/S0103-50532006000300028 | |
学科分类:化学(综合) | |
来源: SciELO | |
【 摘 要 】
A new method for metronidazole determination, based on spectrometric monitoring of a diazonium salt produced in-line by alkaline hydrolysis released nitrite ions, was developed and successfully applied to pharmaceutical tablets (r = 0.9993, 2.0-20.0 mg L-1, DL = 0.7 mg L-1) with no interference from common ingredients accompanying the drug.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912050579951ZK.pdf | 174KB | download |