Diploflavone, a new flavonoid from Diplotropis ferruginea Benth. (Fabaceae)

Journal of the Brazilian Chemical Society

Jackson Roberto G. S. Almeida²  José Maria Barbosa-filho²  Analúcia G. S. Cabral²  Maria De Fátima Agra²  Emidio V. Leitão Da Cunha²  Marcelo S. Da Silva²  Silene C. Do Nascimento¹  Raimundo Braz-filho¹ 

[1] ,Universidade Federal da Paraíba Laboratório de Tecnologia Farmacêutica João Pessoa PB ,Brazil

关键词: Diplotropis ferruginea;    Fabaceae;    flavonoids;    cytotoxicity;   

DOI  :  10.1590/S0103-50532005000800027

来源: SciELO

【 摘 要 】

The chemical examination of Diplotropis ferruginea Benth. resulted in the isolation of a new 3-methoxyflavone, 3-methoxy-6-O-prenyl-6",6"-dimethylchromene-(7,8,2",3")-flavone, to which was given the trivial name diploflavone (1); as well as the known 3,6-dimethoxy-6",6"-dimethylchromene-(7,8,2",3")-flavone (2). The structure of the new compound was established by spectral analyses. Cytotoxic activity of the isolated compounds was tested against the cells NCI-H292 (lung carcinoma), HEp-2 (larynx carcinoma) and KB (oral epidermoid carcinoma). The cells HEp-2 were the most affected by the substances tested.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License