Diploflavone, a new flavonoid from Diplotropis ferruginea Benth. (Fabaceae)

Journal of the Brazilian Chemical Society

Braz-Filho, Raimundo¹  Universidade Estadual da Paraíba, Campina Grande, Brazil¹  Silva, Marcelo S. da¹  Universidade Estadual do Norte Fluminense, Rio de Janeiro, Brazil¹  Cunha, Emidio V. Leitão da¹  Nascimento, Silene C. do¹  Agra, Maria de Fátima¹  Universidade Federal de Pernambuco, Recife, Brazil¹  Barbosa-Filho, José Maria¹  Cabral, Analúcia G. S.¹  Almeida, Jackson Roberto G. S.¹  Universidade Federal da Paraíba, João Pessoa, Brazil¹  Universidade Federal do Vale do São Francisco, Petrolina, Brazil¹ 

关键词: Diplotropis ferruginea;    Fabaceae;    flavonoids;    cytotoxicity;   

DOI  :  10.1590/S0103-50532005000800027

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The chemical examination of Diplotropis ferruginea Benth. resulted in the isolation of a new 3-methoxyflavone, 3-methoxy-6-O-prenyl-6",6"-dimethylchromene-(7,8,2",3")-flavone, to which was given the trivial name diploflavone (1); as well as the known 3,6-dimethoxy-6",6"-dimethylchromene-(7,8,2",3")-flavone (2). The structure of the new compound was established by spectral analyses. Cytotoxic activity of the isolated compounds was tested against the cells NCI-H292 (lung carcinoma), HEp-2 (larynx carcinoma) and KB (oral epidermoid carcinoma). The cells HEp-2 were the most affected by the substances tested.

【 授权许可】

Unknown