Polyketides from the marine sponge Plakortis angulospiculatus

Journal of the Brazilian Chemical Society

Rosângela De A. Epifanio¹  Leandro S. Pinheiro¹  Natalia C. Alves¹ 

[1] ,Universidade Federal Fluminense Instituto de Química Departamento de Química OrgânicaNiterói RJ ,Brazil

关键词: Plakortis angulospiculatus;    brine shrimp assay;    antibacterial;    polyketide;   

DOI  :  10.1590/S0103-50532005000800010

来源: SciELO

【 摘 要 】

Organic extracts of the marine sponge Plakortis angulospiculatus were studied from two different collections from Pernambuco State, Brazil. Bioautography with opportunistic marine pathogens, with results from the brine shrimp lethality assay, were used to guide the purification of the known furanylidenic methyl ester 1 and two new derivatives 2 and 3. The structures were elucidated by spectroscopic methods and by selective reduction of 3 into 2.

【 授权许可】

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