A new neolignan and antioxidant phenols from Nectandra grandiflora

Journal of the Brazilian Chemical Society

Alan B. Ribeiro²  Vanderlan Da S. Bolzani²  Massayoshi Yoshida¹  Leonardo S. Santos¹  Marcos N. Eberlin¹  Dulce H. S. Silva² 

[1],Universidade Estadual Paulista Instituto de Química Araraquara SP ,Brazil

关键词: Nectandra grandiflora;    Lauraceae;    neolignan;    flavonoid;    radical scavenging activity;    antioxidant;   

DOI  :  10.1590/S0103-50532005000400005

来源: SciELO

【 摘 要 】

The EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards b-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (DA 32, 16 and 73% at 50 µmol L-1) and were compared to commercial antioxidants rutin (81% at 50 µmol L-1) and BHT (9% at 50 µmol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1]octane neolignan 2'-oxo-piperol B were obtained and characterized by spectrometric methods.

【 授权许可】

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