Silica sulfuric acid as an efficient and reusable reagent for crossed-aldol condensation of ketones with aromatic aldehydes under solvent-free conditions

Journal of the Brazilian Chemical Society

Peyman Salehi²  Minoo Dabiri¹  Mohammad Ali Zolfigol¹  Mohammad Ali Bodaghi Fard¹ 

[1] ,Shahid Beheshti University Aromatic and Medicinal Plants and Drug Research Institute Department of PhytochemistryTehran,Iran

关键词: crossed-aldol condensation;    silica sulfuric acid;    solid phase;    a;    b-unsaturated carbonyls;   

DOI  :  10.1590/S0103-50532004000500026

来源: SciELO

【 摘 要 】

Aromatic aldehydes undergo crossed-aldol condensation with ketones in the presence of silica sulfuric acid under solvent-free conditions to afford the corresponding a, b-unsaturated aldol products in excellent yields. The reagent is reusable for several times without any decrease in the yield of the reactions.

【 授权许可】

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