Pneumoperitoneum induces morphological alterations in the rat testicle

Acta Cirurgica Brasileira

Carina Teixeira Ribeiro²  Diogo Benchimol De Souza¹  Jorge Luiz Medeiros Jr.¹  Waldemar Silva Costa¹  Marco Aurélio Pereira-sampaio¹  Francisco José Barcellos Sampaio¹ 

[1] ,UERJ Urogenital Research Unit Postgraduate Program in Physiopathology and Surgical SciencesRio de Janeiro,Brazil

关键词: Pneumoperitoneum;    Testis;    Histology;    Rats;   

DOI  :  10.1590/S0102-86502013000600003

来源: SciELO

【 摘 要 】

PURPOSE:To investigate the seminiferous tubule histological morphology after an 8 mmHg pneumoperitoneum in the rat model. METHODS: Fourteen rats were divided into two groups: a Sham group submitted to anesthesia and a pneumoperitoneum (Pp) group submitted to abdominal insufflation at 8 mmHg during three hours, followed by desuflation. All rats were killed after six weeks, testicles were collected and evaluated for the tubule diameter, germinative epithelium height and Johnsen´s score. Means were compared by using the Student's-t-test. RESULTS:The seminiferous tubule diameter was diminished by 11.3% in the group submitted to pneumoperitoneum (p<0.05). No significant difference was found among the groups when analyzing the epithelium height and Johnsen´s score. CONCLUSION:In the rat model, the seminiferous tubules present structural alterations when subjected to pneumoperitoneum of 8 mmHg during three hours.

【 授权许可】

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