An experimental study to compare inflammatory response due to liquid or gas joint distension in horses submitted to arthroscopy

Acta Cirurgica Brasileira

Renata Bello Rossetti¹  Cristina De Oliveira Massoco²  Ana Carolina Alves Penna¹  Luis Claudio Lopes Correia Da Silva¹ 

[1] ,USP Faculty of Veterinary Medicine Department of PathologySao Paulo SP ,Brazil

关键词: Carbon Dioxide;    Synovial Fluid;    Joint Diseases;    Synovitis;    Flow Cytometry;    Horses;    Dióxido de Carbono;    Líquido Sinovial;    Artropatias;    Sinovite;    Citometria de Fluxo;    Cavalos;   

DOI  :  10.1590/S0102-86502012001200004

来源: SciELO

【 摘 要 】

PURPOSE: To assess comparatively the inflammatory response that follows CO2 or Ringer's lactate joint capsular distension of horses submitted to experimental arthroscopy METHODS: Each animal was submitted to a bilateral tarsocrural arthroscopy employing gas distention in one joint and fluid distention in the contralateral joint. Synovial fluid was evaluated at 0, six, 12, 24 and 48 hours post-operative. RESULTS: The use of CO2 for arthroscopy causes an acute and mild synovitis alike to the liquid capsular distension, showing similar synovial fluid increase of leukocytes, TP, and TNF-α. Although synovial fluid PGE2 content was higher in joints submitted to CO2 distension, lower levels of hemoglobin and leukocytes oxidative burst after surgery indicates that CO2 arthroscopy decreased intra-articular bleeding and activation of infiltrating leukocytes. CONCLUSIONS: The use of CO2 for arthroscopic examination causes acute and mild synovitis that is similar to the effects caused by the liquid capsular distension. CO2 also seems to decrease intra-articular bleeding and activation of leukocytes.

【 授权许可】

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