Revista Brasileira de Cirurgia Cardiovascular | |
The behavior of Troponin I and CKMB mass in children who underwent surgical correction of congenital heart malformations | |
Pedro Rafael Salerno1  Fabio Biscegli Jatene1  Patrícia Elias Figueiredo1  Ieda Jatene Bosisio1  Marcelo Biscegli Jatene1  Magaly Arraes Dos Santos1  Luís Carlos Bento De Souza1  Adib Domingos Jatene1  | |
关键词: Troponin I; Creatine kinase; Heart defects; congenital; Magnesium sulfate; Cardioplegic solutions; Troponina I; Creatina quinase; Cardiopatias congênitas; Sulfato de magnésio; Soluções cardioplégicas; | |
DOI : 10.1590/S0102-76382003000300008 | |
来源: SciELO | |
【 摘 要 】
OBJECTIVE: To analyze the behavior of troponin (TROP I) and CKMB mass (CKMBm) in regards to the addition of magnesium in cardioplegic solutions; and also the influence of per-operative factors. METHOD: A total of 28 children with ages ranging from 3 to 108 months were studied. The mean weight was 11.8 kg. Eighteen were male. The patients were divided into two groups. Sixteen children in group I (GI) and 12 in group II (GII). The patients in GI received cold blood cardioplegic solution with magnesium (12 mEq/L) and potassium chloride (20 mEq/L) at 20 mL/kg. The patients in GII received the same solution without magnesium. Six blood samples were collected for serum analysis of the concentration of TROP I and CKMBm. The blood samples were collected before clamping the aorta and at 1, 6, 24, 48 and 72 hours after aorta clamping termination. RESULTS: There were no statistical differences in the TROP I and CKMBm levels between the two groups. Among the per-operative factors cyanosis influenced the TROP I and CKMBm levels. Additionally, the aorta clamping time influenced the TROP I levels. CONCLUSIONS: The addition of magnesium in the cardioplegic solution was not associated with different levels of TROP I and CKMBm. Cyanosis and aorta clamping time interfered with peak TROP I levels.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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