Pyrimidine alkaloids from Eudistoma vannamei

Revista Brasileira de Farmacognosia

Renata Takeara¹  Thiago Olitta Basso¹  Paula Christine Jimenez¹  Letícia Veras Costa-lotufo¹  Norberto Peporine Lopes¹  João Luis Callegari Lopes¹ 

关键词: Pyrimidine;    Tunicate;    Steroids;    Nucleosides;   

DOI  :  10.1016/j.bjp.2015.08.001

来源: SciELO

【 摘 要 】

Abstract Methanolic extracts of the Brazilian endemic ascidian Eudistoma vannamei have been extensively studied for their cytotoxic activity against several human cancer cell lines. Previous work reported the occurrence of purine derivatives and staurosporine alkaloids as the major nitrogen-containing compounds. In this study, we report the occurrence of three pyrimidine alkaloids in addition to cholesterol, sitosterol and stigmasterol.

【 授权许可】

CC BY-NC-ND   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License