Two new diterpenoids from Leonurus japonicus

Revista Brasileira de Farmacognosia

Hankui Wu¹  Sensheng Wang¹  Haijuan Liu¹  Yan E¹  Yan Li¹  Ruijin Liu¹  Jinjin Wang¹  Zhiyong Xu¹  Yanyan Lv¹  Shanshan Sun¹  Gang Li¹  Yunfeng Shi¹ 

关键词: Leonurus japonicus;    Labdane diterpenoid;   

DOI  :  10.1016/j.bjp.2015.02.006

来源: SciELO

【 摘 要 】

Abstract Two new labdane-type diterpenoids, 5-ethoxy-3-(2-((R)-4-hydroxy-2,5,5,8a-tetramethyl-3-oxo-3,5,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)furan-2(5H)-one (1), and 5-hydroxy-4-(2-((1R,3S,7aS)-1-hydroxy-4,4,7a-trimethyl-3-propionyloctahydroisobenzofuran-1-yl)ethyl)furan-2(5H)-one (2), were isolated from the EtOH extract of the herb of Leonurus japonicus Houtt., Lamiaceae. Their chemical structures were determined by analysis of 1D, 2D NMR, HRESIMS, and by comparison with known analogs.

【 授权许可】

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