Evaluation of larvicidal activity of the methanolic extracts of Piper alatabaccum branches and P. tuberculatum leaves and compounds isolated against Anopheles darlingi

Revista Brasileira de Farmacognosia

Frances T. T. Trindade²  Rodrigo G. Stabeli¹  Valdir A. Facundo¹  Consuelo T. Cardoso¹  Minelly A. Da Silva¹  Luiz H. S. Gil¹  Izaltina Silva-jardim¹  Alexandre De Almeida E Silva² 

[1] ,Universidade Federal de Rondônia Departamento de Biologia Laboratório de Bioecologia de Insetos,Brazil

关键词: cinnamic acid;    dihydropiplartine;    flavone;    insecticide;    piplartine;    piperamides;   

DOI  :  10.1590/S0102-695X2012005000039

来源: SciELO

【 摘 要 】

Piper is a notable genus among Piperaceae due to their secondary metabolites such as lignans, amides, esters and long chain fatty acids used as anti-herbivore defenses with comparable effects of pyrethroids, that holds a promise in insect control, including malaria vectors such as Anopheles darlingi, the main vector in the North of Brazil. Methanolic extracts of Piper tuberculatum Jacq., Piperaceae, and P. alatabaccum Trel. & Yunck., Piperaceae, and some isolated compounds, i.e, 3,4,5-trimetoxy-dihydrocinamic acid, dihydropiplartine; piplartine, piplartine-dihydropiplartine and 5,5',7-trimetoxy-3',4'-metilenodioxiflavone were tested as larvicides against A. darlingi. The Lethal Concentrations (LC50 and LC90) of methanolic extracts were 194 and 333 ppm for P. tuberculatum and 235 and 401 ppm for P. alatabacum, respectively. Isolated compounds had lower LC values, e.g. the LC50 and LC90 of the piplartine-dihidropiplartine isolated from both plant species was 40 and 79 ppm, respectively.

【 授权许可】

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