Evaluation of antimalarial, free-radical-scavenging and insecticidal activities of Artemisia scoparia and A. Spicigera, Asteraceae

Revista Brasileira de Farmacognosia

Fariba H. Afshar²  Abbas Delazar²  Omar Janneh¹  Hossein Nazemiyeh¹  Ardalan Pasdaran¹  Lutfun Nahar¹  Satyajit D. Sarker¹ 

[1] ,Tabriz University of Medical Sciences Drug Applied Research CenterTabriz ,Iran

关键词: Artemisia scoparia;    Artemisia spicigera;    Asteraceae;    DPPH;    antimalaria;    insecticide;   

DOI  :  10.1590/S0102-695X2011005000144

来源: SciELO

【 摘 要 】

Artemisia species (Asteraceae), widespread throughout the world, are a group of important medicinal plants. The extracts of two medicinal plants of this genus, Artemisia scoparia Waldst. & Kit. and A. spicigera C. Koch, were evaluated for potential antimalarial, free-radical-scavenging and insecticidal properties, using the heme biocrystallisation and inhibition assay, the DPPH assay and the contact toxicity bioassay using the pest Tribolium castaneum, respectively. The methanol extracts of both species showed strong free-radical-scavenging activity and the RC50 values were 0.0317 and 0.0458 mg/mL, respectively, for A. scoparia and A. spicigera. The dichloromethane extracts of both species displayed a moderate level of potential antimalarial activity providing IC50 at 0.778 and 0.999 mg/mL for A. scoparia and A. spicigera, respectively. Both species of Artemisia showed insecticidal properties. However, A. spicigera was more effective than A. scoparia.

【 授权许可】

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