Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa

Revista Brasileira de Farmacognosia

Helena O. Ferraz²  Magali G. Silva²  Rui Carvalho¹  Ivana B. Suffredini¹  Edna T. M. Kato¹  Fernanda Arakaki¹  Elfriede M. Bacchi¹ 

[1] ,University of SorocabaSorocaba SP ,Brazil

关键词: Cuscuta racemosa;    Convolvulaceae;    antimicrobial activity;    cytotoxicity;   

DOI  :  10.1590/S0102-695X2011005000005

来源: SciELO

【 摘 要 】

Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test.

【 授权许可】

CC BY-NC-ND   
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