Antimicrobial activity of Mimosa tenuiflora (Willd.) Poir. from Northeast Brazil against clinical isolates of Staphylococcus aureus

Revista Brasileira de Farmacognosia

Itácio Q. M. Padilha²  Andréia V. Pereira¹  Onaldo G. Rodrigues¹  José P. Siqueira-júnior²  Maria Do Socorro V. Pereira² 

[1] ,Universidade Federal da Paraíba Departamento de Biologia Molecular João Pessoa PB ,Brasil

关键词: Mimosa tenuiflora;    ethanol extract;    antimicrobial activity;    Staphylococcus aureus;    Mimosa tenuiflora;    extrato etanólico;    atividade antimicrobiana;    Staphylococcus aureus;   

DOI  :  10.1590/S0102-695X2010000100010

来源: SciELO

【 摘 要 】

Mimosa tenuiflora is a native plant of Northeast Brazil where it is popularly known as ''jurema-preta'' and it is widely used in folk medicine. In this work the anti-Staphylococcus aureus activity of ethanol extract of M tenuiflora was evaluated by determination of minimum inhibitory concentration (MIC) of clinical isolates by the agar dilution method, and by time-kill assay using a reference strain. MIC values against 30 isolates were 0,18 mg/mL (16/30) or 0,36 mg/mL (14/30, and also the reference strain). In the reference strains, at concentrations up to 4x MIC, only bacteriostatic effect was observed, but at 8x MIC a fast bactericidal effect was observed.

【 授权许可】

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