Chemical constituents from Swartzia apetala Raddi var. glabra and evaluation of their antifungal activity against Candida spp.

Revista Brasileira de Farmacognosia

Marcelo Francisco De Araujo²  Ivo José Curcino Vieira²  Raimundo Braz-filho²  Olney Vieira-da-motta¹  Leda Mathias² 

[1] ,Universidade Estadual do Norte Fluminense Setor de Química de Produtos Naturais Campos dos Goytacazes RJ ,Brazil

关键词: Swartzia apetala;    antifungal activity;    stilbene;    flavonoids;    terpenoids;    Swartzia apetala;    atividade antifúngica;    estilbeno;    flavonoides;    terpenóides;   

DOI  :  10.1590/S0102-695X2009000300005

来源: SciELO

【 摘 要 】

From the hexanic extract of the stem from Swartzia apetala Raddi var. glabra were isolated one stilbene (1), one flavanone (2), one pterocarpan (3), one triterpene (4) and a mixture of three steroids (5 to 7). The crude extract and the compounds isolated were submitted to evaluation of the antifungal activity against nine yeast standard ATCC of the Candida genus. Among the compounds only the triterpene (4) and the mixture of steroids (5 to 7) showed no activity. The structures of the compounds were determined by spectral data analysis of GC/MS and ¹H and 13C NMR (1D and 2D experiments), as well as comparison with literature values.

【 授权许可】

CC BY-NC-ND   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License