Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)

Revista Brasileira de Farmacognosia

Nina C. B. Silva²  Maria A. Esquibel²  Iura M. Alves¹  Eudes S. Velozo¹  Mara Z. Almeida¹  Jaci E. S. Santos¹  Fátima De Campos-buzzi¹  Aleandra V. Meira¹  Valdir Cechinel-filho¹ 

[1] ,Universidade Federal do Rio de Janeiro Centro de Ciências da Saúde Programa de Pós-Graduação em Biotecnologia VegetalRio de Janeiro RJ ,Brazil

关键词: Abarema cochliacarpos;    analgesic effects;    medicinal plant;    ytochemical profile;    Abarema cochliacarpos;    Mimosaceae;    atividade analgésica;    plantas medicinais;    perfil fitoquímico;   

DOI  :  10.1590/S0102-695X2009000100011

来源: SciELO

【 摘 要 】

In this study, we investigated the analgesic activity of crude aqueous and methanol extracts obtained from Abarema cochliacarpos bark in mice, and analyzed its phytochemical profile. All the extracts exhibited analgesic properties against the writhing test in mice, but the aqueous and methanol extracts were more active, and more potent than two known analgesic and anti-inflammatory drugs used as reference. They were also active against the capsaicin-model, but inactive when evaluated in the hot-plate test. Phytochemical studies revealed the presence of saponins, catechins, tannins, phenols and anthraquinones.

【 授权许可】

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