Plants with anticonvulsant properties: a review

Revista Brasileira de Farmacognosia

Lucindo J. Quintans Júnior²  Jackson R.g.s. Almeida¹  Julianeli T. Lima¹  Xirley P. Nunes¹  Jullyana S. Siqueira²  Leandra Eugênia Gomes De Oliveira¹  Reinaldo N. Almeida¹  Petrônio F. De Athayde-filho¹  José M. Barbosa-filho¹ 

[1] ,Universidade Federal de Sergipe Departamento de Fisiologia São Cristóvão SE ,Brazil

关键词: Medicinal plants;    Natural products;    convulsion;    anticonvulsant properties;    animal models;    review;    Plantas medicinais;    Produtos naturais;    convulsão;    atividade anticonvulsivante;    modelos animais;    revisão;   

DOI  :  10.1590/S0102-695X2008000500026

来源: SciELO

【 摘 要 】

Seizures are resistant to treatment with currently available anticonvulsant drugs in about 1 out of 3 patients with epilepsy. Thus, there is a need for new, more effective anticonvulsant drugs for intractable epilepsy. However, nature is a rich source of biological and chemical diversity and a number of plants in the world have been used in traditional medicine remedies, i.e., anticonvulsant, anxiolytic, analgesic, antidepressant. This work constitutes a literature review on medicinal plants showing anticonvulsant properties. The review refers to 16 Brazilian plants and a total 355 species, their families, geographical distribution, the utilized parts, method and references. Some aspects of research on medicinal plants and a brief review of the most common animal models to discover antiepileptic drugs are discussed. For this purpose over 170 references were consulted.

【 授权许可】

CC BY-NC-ND   
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