Antidiarrhoeal effects of Mikania glomerata Spreng. (Asteraceae) leaf extract in mice

Revista Brasileira de Farmacognosia

Hérida R.n. Salgado¹  Ana Flávia F. Roncari¹  Raquel R.d. Moreira¹ 

[1] ,Universidade Estadual Paulista Faculdade de Ciências Farmacêuticas Araraquara SP ,Brasil

关键词: Mikania glomerata;    Asteraceae;    guaco;    intestinal motility;   

DOI  :  10.1590/S0102-695X2005000300007

来源: SciELO

【 摘 要 】

Mikania glomerata Spreng. (Asteracae) is a plant widely used to treat gastrointestinal disorders in Brazilian traditional medicine. In the present work, an aqueous extract of the leaves of Mikania glomerata has shown a decrease in the propulsive movements of the intestinal contents in mice. Oral administration produced an inhibition of gastrointestinal transit as effective as that produced by loperamide. These findings suggested that the aqueous extract of the leaves of Mikania glomerata might elicit an antidiarrhoeal effect by inhibiting intestinal motility.

【 授权许可】

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