Combined liver-kidney transplantation: experience at a brazilian university hospital

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

Francisca Jovita De Oliveira Veras¹  Gustavo Rêgo Coelho¹  Bartolomeu Alves Feitosa-neto¹  João Batista Gadelha Cerqueira¹  Regina Célia F. Gomes Garcia¹  José Huygens Parente Garcia¹ 

关键词: Kidney transplantation;    Liver transplantation;    Survival;    Transplante renal;    Transplante hepático;    Sobrevida;   

DOI  :  10.1590/S0102-67202014000100013

来源: SciELO

【 摘 要 】

Background: Combined liver-kidney transplant is a routine procedure in many transplant centers. The increase in its number coincided with the introduction in 2002 of the MELD (Model for End-stage Liver Disease) score for allocation of livers, prioritizing patients with renal dysfunction.Aim : To analyze the experience with combined liver-kidney transplantation in a liver transplant center in Brazil.Method : A retrospective review was conducted. All transplants were performed using grafts from deceased donors.Results : Sixteen combined liver-kidney transplantations were performed in the same period, which corresponds to 2.7% and 2.5% of the kidney and liver transplants, respectively. Fourteen patients were male (87.5 %) and two were female (12.5%). The average patients and donors age was 57.3±9.1 and 32.7±13.1, respectively. The MELD score mean was 23.6±3.67. The main cause of liver dysfunction were chronic hepatitis C virus (n=9). As for renal dysfunction, diabetic nephropathy (n=4) was the most frequent. There were six deaths, two of them by severe dysfunction of the liver graft and four by infectious causes. The 1, 3 and 5 years survival rate in patients undergoing liver-kidney transplantations was 68.8%, 57.3% and 57.3%, respectively.Conclusion : The survival rates achieved in this series are considered satisfactory and show that this procedure has an acceptable morbidity and survival.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License