Maternal obesity and offspring body composition by indirect methods: a systematic review and meta-analysis

Cadernos de Saúde Pública

Helen Castillo-laura¹  Iná S. Santos¹  Lenice C. M. Quadros¹  Alicia Matijasevich¹ 

关键词: Obesity;    Pregnancy;    Body Composition;    Adiposity;    Obesidad;    Embarazo;    Composición Corporal;    Adiposidad;    Obesidade;    Gravidez;    Composição Corporal;    Adiposidade;   

DOI  :  10.1590/0102-311X00159914

来源: SciELO

【 摘 要 】

Abstract This study reviewed the evidence that assessed the association between maternal pre-pregnancy body mass index (BMI) and/or gestational weight gain and offspring body composition in childhood. A systematic review was conducted. Cohort studies, case-control studies and randomized controlled trials measuring offspring body composition by indirect methods were included. Meta-analyses of the effect of pre-pregnancy BMI on offspring fat-free mass, body fat percent, and fat mass were conducted through random-effects models. 20 studies were included, most of which reported a positive association of pre-pregnancy BMI with offspring body fat. Standardized mean differences in body fat percent, fat mass and fat-free mass between infants of women with normal pre-pregnancy BMI and those of overweight/obese women were 0.31 percent points (95%CI: 0.19; 0.42), 0.38kg (95%CI: 0.26; 0.50), and 0.18kg (95%CI: -0.07; 0.42), respectively. Evidence so far suggests that pre-pregnancy maternal overweight is associated with higher offspring adiposity.

【 授权许可】

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