The Acre Project: the epidemiology of malaria and arthropod-borne virus infections in a rural Amazonian population

Cadernos de Saúde Pública

Mônica Da Silva-nunes²  Rosely Dos Santos Malafronte¹  Bruna De Almeida Luz²  Estéfano Alves De Souza²  Lívia Carício Martins¹  Sueli Guerreiro Rodrigues¹  Jannifer Oliveira Chiang¹  Pedro Fernando Da Costa Vasconcelos¹  Pascoal Torres Muniz¹  Marcelo Urbano Ferreira² 

[1] ,Universidade de São Paulo Instituto de Ciências Biomédicas São Paulo,Brasil

关键词: Malaria;    Dengue;    Arboviruses;    Arbovirus Infections;    Amazonian Ecosystem;    Malária;    Dengue;    Arbovírus;    Infecções por Arbovirus;    Ecossistema Amazônico;   

DOI  :  10.1590/S0102-311X2006000600021

来源: SciELO

【 摘 要 】

The authors describe the baseline malaria prevalence and arbovirus seroprevalence among 467 subjects in an ongoing cohort study in rural Amazonia. Most subjects (72.2%) reported one or more previous episodes of malaria, and 15.6% had been hospitalized for malaria, but only 3.6% of individuals five years or older had malaria parasites detected by microscopy (10 with Plasmodium vivax and 4 with P. falciparum). Antibodies to Alphavirus, Orthobunyavirus, and/or Flavivirus were detected by hemagglutination inhibition (HI) in 42.6% of subjects aged five years or older, with a higher seropositivity rate among males (49.2%) than females (36.2%). Since 98.9% of subjects had been immunized for yellow fever, the presence of cross-reactive antibodies to dengue and other Flaviviruses cannot be ruled out, but at least 12 subjects (3.3%) with IgM antibodies to dengue virus detected by ELISA had a putative recent exposure to this virus.

【 授权许可】

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