Estudo exploratório da associação entre o perfil lipídico e a densidade mineral óssea em mulheres menopausadas, em hospital de referência de Campinas

Cadernos de Saúde Pública

Silval Fernando Cardoso Zabaglia¹  Adriana Orcesi Pedro¹  Aarão Mendes Pinto Neto¹  Telma Guarisi¹  Lucia Helena Simões Da Costa Paiva¹  Eduardo Lane¹ 

[1] ,Universidade Estadual de CampinasCampinas SP ,Brasil

关键词: Menopause;    Osteoporosis;    Cardiovascular Disease;    Menopausa;    Osteoporose;    Sistema Cardiovascular;   

DOI  :  10.1590/S0102-311X1998000400019

来源: SciELO

【 摘 要 】

A total of 72 postmenopausal patients presenting no risk factors for cardiovascular disease nor osteoporosis, were studied. The study evaluated total serum cholesterol and fractions and bone mass by densitometry of the lumbar spine and femur using a Lunar-DPX. There was no association between lipid profile variables and bone mineral density, except for high density lipoprotein (HDL), which showed an inverse correlation (p = 0.001). Multiple regression showed that total cholesterol levels higher than 240 mg% had a positive association with BMD (p = 0.026). In addition, the ratio between LDL and HDL (Castelli 2 index) showed a negative association with BMD (p = 0.002). The diagnostic validation test showed that all lipid profile variables had low sensitivity and specificity as indicators for osteoporosis. The conclusions were that lipid profile variables did not show a significant association with bone mass and could not be used as indicators for bone mineral density.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License