Pasteurella multocida type A as the primary agent of pneumonia and septicaemia in pigs

Pesquisa Veterinária Brasileira

João X. De Oliveira Filho¹  Marcos A.z. Morés¹  Raquel Rebelatto¹  Alais M.d. Agnol¹  Camila L.a. Plieski¹  Catia S. Klein¹  David E.s.n. Barcellos¹  Nelson Morés¹ 

关键词: Swine pasteurellosis;    necrosuppurative pleuropneumonia;    sepsis.;    Pasteurelose suína;    pleuropneumonia necrossupurativa;    septicemia.;   

DOI  :  10.1590/S0100-736X2015000800003

来源: SciELO

【 摘 要 】

Abstract: In order to understand better the pathological aspects and spread of Pasteurella multocida type A as the primary cause of pneumonia in pigs, was made an experiment with intranasal inoculation of different concentrations of inocula [Group (G1): 108 Colony Forming Units (CFU)/ml; G2: 107 CFU/ml; G3: 106 CFU/ml and G4: 105 CFU/ml], using two pigs per group. The pigs were obtained from a high health status herd. Pigs were monitored clinically for 4 days and subsequently necropsied. All pigs had clinical signs and lesions associated with respiratory disease. Dyspnoea and hyperthermia were the main clinical signs observed. Suppurative cranioventral bronchopneumonia, in some cases associated with necrosuppurative pleuropneumonia, fibrinous pericarditis and pleuritic, were the most frequent types of lesion found. The disease evolved with septicaemia, characterized by septic infarctions in the liver and spleen, with the detection of P. multocida type A. In this study, P. multocida type A strain #11246 was the primary agent of fibrinous pleuritis and suppurative cranioventral bronchopneumonia, pericarditis and septicaemia in the pigs. All concentrations of inoculum used (105-108 CFU/ml) were able to produce clinical and pathological changes of pneumonia, pleuritis, pericarditis and septicemia in challenged animals.

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