Effects of zearalenone in prepubertal gilts

Pesquisa Veterinária Brasileira

Letícia C. Teixeira¹  Fabiano Montiani-ferreira¹  Rosângela Locatelli-dittrich¹  Elizabeth Santin¹  Geraldo C. Alberton¹ 

关键词: Swine;    zearalenone;    mycotoxin;    uterus;    vagina;    humoral immune response;    Suínos;    zearalenona;    micotoxina;    útero;    vagina;    resposta imune humoral;   

DOI  :  10.1590/S0100-736X2011000800004

来源: SciELO

【 摘 要 】

Prepubertal gilts were fed with a diet containing zearalenone (ZEA) in a concentration of 0.75 mg/kg for 21 days. The effects of this mycotoxin on morphologic aspects of the reproductive tract as well as on complete blood count (CBC), serum biochemistry analysis (SBA) and humoral immune response against sheep red blood cells (SRBC) were evaluated. There was a significant increase (P<0.05) on the reproductive tract weight, vulvar area, height of the epithelial cells of endometrial glands and uterine mucosa. These results showed the ability of this nonsteroidal mycotoxin in mimicking actions of 17β estradiol at the concentration of 0.75mg/kg. No changes in weight gain, CBC, SBA parameters and humoral response against SRBC were observed.

【 授权许可】

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