Haematological and biochemical characteristics of the splenic effluent blood in schistosomal patients undergoing splenectomy

Revista do Colégio Brasileiro de Cirurgiões

Andy Petroianu¹  Kelly Cristine De Lacerda Rodrigues Buzatti¹  Vivian Resende¹  Kelly Renata Sabino¹ 

关键词: Blood;    Spleen;    Blood cells;    Portal hypertension;    Blood transfusion;    autologous;    Splenic vein;    Sangue;    Baço;    Células sanguíneas;    Hipertensão portal;    Transfusão de sangue autóloga;    Veia esplênica;   

DOI  :  10.1590/S0100-69912014000300007

来源: SciELO

【 摘 要 】

OBJECTIVE: To assess hematological and biochemical features of splenic effluent blood and their influence on the rise of hematological values after splenectomy.METHODS: we studied 20 patients undergoing surgical treatment for schistosomatic portal hypertension. We collected blood samples for CBC, coagulation, bilirubin and albumin in the splenic vein (perioperative) and peripheral blood (immediately pre and postoperative periods).RESULTS: the splenic blood showed higher values of red blood cells, hemoglobin, hematocrit, platelet count, total leukocytes, neutrophils, lymphocytes, monocytes, eosinophils and basophils, as well as reduction of laboratory coagulation parameters in relation to peripheral blood collected preoperatively. In the postoperative peripheral blood there was an increase in the overall leukocytes and in their neutrophil component, and decreased levels of basophils, eosinophils and lymphocytes. The other postoperative variables of complete blood count and coagulation tests were not different compared with the splenic blood. The albumin values were lower postoperatively when compared to preoperative and splenic blood. There were higher values of direct bilirubin in the postoperative period when compared with the preoperative and splenic blood. Postoperative indirect bilirubin was lower compared to its value in the splenic blood.CONCLUSION: hematological and biochemical values of splenic effluent blood are higher than those found in peripheral blood in the presence of schistosomal splenomegaly. However, the splenic blood effluent is not sufficient to raise the blood levels found after splenectomy.

【 授权许可】

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