Flavonoides glicosilados de Erythroxylum pulchrum a. st.-hil. (Erythroxylaceae)

Química Nova

Camila Holanda De Albuquerque²  Josean Fechine Tavares²  Steno Lacerda De Oliveira²  Tainá Souza Silva²  Gregório Fernandes Gonçalves¹  Vicente Carlos De Oliveira Costa²  Maria De Fátima Agra¹  Hilzeth De Luna Freire Pessôa¹  Marcelo Sobral Da Silva¹ 

[1] ,Universidade Federal da Paraíba Centro de Ciências da Saúde Departamento de Ciências FarmacêuticasJoão Pessoa PB ,Brasil

关键词: Erythroxylum pulchrum;    flavonoid glycosides;    antimicrobial activity;   

DOI  :  10.5935/0100-4042.20140104

来源: SciELO

【 摘 要 】

The phytochemical investigation of Erythroxylum pulchrum St. Hil. (Erythroxylaceae) led to the isolation of three known flavonoid glycosides quercetin-3-O-α-L-rhaminoside, ombuin-3-ruthinoside and ombuin-3-ruthinoside-5-glucoside. These flavonoids are being described for the first time in this E. pulchrum. The structures of the compounds were determined by analysis of IR, MS and NMR data, as well as by comparison with literature data. The methanolic extract of leaves from E. pulchrum inhibited the growth of the Bacillus subtilis CCT 0516, Escherichia coli ATCC 2536, Pseudomonas aeruginosa ATCC 8027, P. aeruginosa ATCC 25619, Staphylococcus aureus ATCC 6538, S. aureus ATCC 25925, Streptococcus sanguinis ATCC 15300, S. salivarius ATCC 7073, S. mutans ATCC 25175 and Streptococcus ATCC. S. aureus ATCC 25925 was the most sensitive among the other S. sanguinis while S. salivarius proved the most resistant.

【 授权许可】

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