Flavonoid glycosides from Erythroxylum pulchrum a. st.-hil. (Erythroxylaceae)

Química Nova

Albuquerque, Camila Holanda de¹  Silva, Marcelo Sobral da¹  Agra, Maria de Fátima¹  Pessôa, Hilzeth de Luna Freire¹  Universidade Federal da Paraíba, João Pessoa, Brasil¹  Costa, Vicente Carlos de Oliveira¹  Oliveira, Steno Lacerda de¹  Tavares, Josean Fechine¹  Silva, Tainá Souza¹  Gonçalves, Gregório Fernandes¹ 

关键词: Erythroxylum pulchrum;    flavonoid glycosides;    antimicrobial activity.;   

DOI  :  10.5935/0100-4042.20140104

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The phytochemical investigation of Erythroxylum pulchrum St. Hil. (Erythroxylaceae) led to the isolation of three known flavonoid glycosides quercetin-3-O-α-L-rhaminoside, ombuin-3-ruthinoside and ombuin-3-ruthinoside-5-glucoside. These flavonoids are being described for the first time in this E. pulchrum. The structures of the compounds were determined by analysis of IR, MS and NMR data, as well as by comparison with literature data. The methanolic extract of leaves from E. pulchrum inhibited the growth of the Bacillus subtilis CCT 0516, Escherichia coli ATCC 2536, Pseudomonas aeruginosa ATCC 8027, P. aeruginosa ATCC 25619, Staphylococcus aureus ATCC 6538, S. aureus ATCC 25925, Streptococcus sanguinis ATCC 15300, S. salivarius ATCC 7073, S. mutans ATCC 25175 and Streptococcus ATCC. S. aureus ATCC 25925 was the most sensitive among the other S. sanguinis while S. salivarius proved the most resistant.

【 授权许可】

Unknown