Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental

Química Nova

Cláudia Hoffmann Kowalski¹  Fabio Augusto¹  Helena Teixeira Godoy² 

[1] ,Universidade Estadual de Campinas Instituto de Química Campinas SP ,Brasil

关键词: PCBs;    SPME;    Doehlert design;   

DOI  :  10.1590/S0100-40422013000300018

来源: SciELO

【 摘 要 】

The convenience of the multivariate optimization of SPME procedures through ANOVA calculated using Doehlert designs has been demonstrated for twelve PCBs in the complex matrix of milk. For this study, the main parameters of the extraction were selected and valued through univariate and multivariate optimization. In addition, the analysis of variance allowed identification of the statistically significant variables in this model: high temperature (95 ºC) and ionic strength (36% m/v) proved significant for all the PCBs while intermediate time (70 min) and low methanol concentration (5% v/v) also contributed to the extraction of the majority of these PCBs.

【 授权许可】

CC BY-NC   
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