Licanol, um novo flavanol, e outros constituintes de Licania macrophylla Benth

Química Nova

Fernando Antônio De Medeiros²  Alessandra A. N. Medeiros²  Josean Fechine Tavares¹  José Maria Barbosa Filho¹  Edeltrudes De Oliveira Lima¹  Marcelo Sobral Da Silva¹ 

[1] ,Instituto de Pesquisas Científicas e Tecnológicas do AmapáMacapá AP ,Brasil

关键词: Licania macrophylla;    Chrysobalanaceae;    (-)-4'-O-methyl-epigallocatechin-3'-O-α-L-rhamnoside;   

DOI  :  10.1590/S0100-40422012000600021

来源: SciELO

【 摘 要 】

The phytochemical investigation of L. macrophylla Benth led to the isolation of a new flavanol named licanol: (-)-4'-O-methyl-epigallocatechin-3'-O-α-L-rhamnoside, along with nine known compounds, identified as: (-)-4'-O-methyl-epigallocatechin, pheophytin A, 13²-hydroxy-(13²-S)-pheophytin A, pheophytin B, sitosterol, stigmasterol, sitosterol-β-O-glucoside, betulinic alcohol and oleanolic acid. The structures were established based on IR, HR-ESI-MS, and NMR spectrometric data analysis with the aid of 2D techniques. The methanolic extracts of leaves and stem bark as well as the compounds licanol, 13²-hidroxi-(13²-S)-feofitina A, and betulinic alcohol demonstrated antimicrobial activity against several bacterial strains.

【 授权许可】

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