Quimica nova | |
Licanol, a new flavanol, and other constituents from the Licania macrophylla Benth | |
Medeiros, Fernando Antônio de1  Medeiros, Alessandra A. N.1  Barbosa Filho, José Maria2  Silva, Marcelo Sobral da2  Lima, Edeltrudes de Oliveira2  Tavares, Josean Fechine2  | |
[1] Instituto de Pesquisas Científicas e Tecnológicas do Amapá, Macapá, Brasil;Universidade Federal da Paraíba, João Pessoa, Brasil | |
关键词: Licania macrophylla; Chrysobalanaceae; (-; )-; 4'-; O-; methyl-; epigallocatechin-; 3'-; O-; α; -; L-; rhamnoside.; | |
DOI : 10.1590/S0100-40422012000600021 | |
学科分类:化学(综合) | |
来源: Sociedade Brasileira de Quimica | |
【 摘 要 】
The phytochemical investigation of L. macrophylla Benth led to the isolation of a new flavanol named licanol: (-)-4'-O-methyl-epigallocatechin-3'-O-α-L-rhamnoside, along with nine known compounds, identified as: (-)-4'-O-methyl-epigallocatechin, pheophytin A, 132-hydroxy-(132-S)-pheophytin A, pheophytin B, sitosterol, stigmasterol, sitosterol-β-O-glucoside, betulinic alcohol and oleanolic acid. The structures were established based on IR, HR-ESI-MS, and NMR spectrometric data analysis with the aid of 2D techniques. The methanolic extracts of leaves and stem bark as well as the compounds licanol, 132-hidroxi-(132-S)-feofitina A, and betulinic alcohol demonstrated antimicrobial activity against several bacterial strains.
【 授权许可】
CC BY
【 预 览 】
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RO201902011625354ZK.pdf | 314KB | download |