Licanol, a new flavanol, and other constituents from the Licania macrophylla Benth

Quimica nova

Medeiros, Fernando Antônio de¹  Medeiros, Alessandra A. N.¹  Barbosa Filho, José Maria²  Silva, Marcelo Sobral da²  Lima, Edeltrudes de Oliveira²  Tavares, Josean Fechine² 

[1] Instituto de Pesquisas Científicas e Tecnológicas do Amapá, Macapá, Brasil;Universidade Federal da Paraíba, João Pessoa, Brasil

关键词: Licania macrophylla;    Chrysobalanaceae;    (-;    )-;    4'-;    O-;    methyl-;    epigallocatechin-;    3'-;    O-;    α;    -;    L-;    rhamnoside.;   

DOI  :  10.1590/S0100-40422012000600021

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The phytochemical investigation of L. macrophylla Benth led to the isolation of a new flavanol named licanol: (-)-4'-O-methyl-epigallocatechin-3'-O-α-L-rhamnoside, along with nine known compounds, identified as: (-)-4'-O-methyl-epigallocatechin, pheophytin A, 132-hydroxy-(132-S)-pheophytin A, pheophytin B, sitosterol, stigmasterol, sitosterol-β-O-glucoside, betulinic alcohol and oleanolic acid. The structures were established based on IR, HR-ESI-MS, and NMR spectrometric data analysis with the aid of 2D techniques. The methanolic extracts of leaves and stem bark as well as the compounds licanol, 132-hidroxi-(132-S)-feofitina A, and betulinic alcohol demonstrated antimicrobial activity against several bacterial strains.

【 授权许可】

CC BY