HIV: mecanismo de replicação, alvos farmacológicos e inibição por produtos derivados de plantas

Química Nova

Roberta Costa Santos Ferreira²  Alessandro Riffel¹  Antônio Euzébio Goulart Sant'ana¹ 

[1] ,Universidade Federal de Alagoas Instituto de Ciências Biológicas e da Saúde Maceió AL ,Brasil

关键词: HIV;    natural products;    antiviral;   

DOI  :  10.1590/S0100-40422010000800023

来源: SciELO

【 摘 要 】

The AIDS epidemy has spread out and led to the diversification on the research for new antiviral drugs. Natural products, especially those derived from plants, are well-recognized as excellent sources of new drugs. Several of them have inhibitory activity against HIV replication, and some have been already clinically tested, with favorable results. This review presents the biochemical basis of the viral cycle and the research up to date on the identification, determination of the mechanism of biological action together with the therapeutical potential of plants-derived natural products, in the inhibition of HIV.

【 授权许可】

CC BY-NC   
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