Determinação espectrofotométrica de hexametilenotetramina (HMT) em medicamentos, utilizando ácido cromotrópico e forno de micro-ondas

Química Nova

Enelton Fagnani¹  Leonardo Pezza²  Helena Redigolo Pezza² 

[1] ,Universidade Estadual de Campinas Faculdade de Engenharia Civil, Arquitetura e Urbanismo Campinas SP ,Brasil

关键词: hexamethylenetetramine;    chromotropic acid;    microwave oven;   

DOI  :  10.1590/S0100-40422009000900039

来源: SciELO

【 摘 要 】

This paper proposes a methodology for spectrophotometric determination of hexamethylenetetramine (HMT) by using chromotropic acid in a phosphoric acid media employing a domestic microwave oven as a source of heating. The reddish-purple soluble product is quantitatively formed after 30 s of irradiation and obeys the Beer´s law in the range between 0.1-1.2 mg L-1 HMT (r = 0.99925). The method was applied successfully in commercial pharmaceutical preparations containing dyes in their composition. The results showed that the method proposed is feasible for simplicity, speed, low cost, precision and accuracy when compared with United States Pharmacopeia official method.

【 授权许可】

CC BY-NC   
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