Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A

Química Nova

Edson Dos Anjos Dos Santos²  Adilson Beatriz²  Dênis Pires De Lima²  Maria Rita Marques¹  Carla Braga Leite¹ 

[1] ,Universidade Federal Mato Grosso do Sul Centro de Ciências Exatas e Tecnlogia Departamento de QuímicaCampo Grande MS ,Brasil

关键词: resorcinolic lipid;    cytosporone A;    allelopathic activity;   

DOI  :  10.1590/S0100-40422009000700032

来源: SciELO

【 摘 要 】

Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License