Polímeros com capacidade de reconhecimento molecular no controlo da libertação de fármacos. Parte 1: síntese e caracterização

Química Nova

Margarita Domingues Sousa²  Carlos Maurício Barbosa¹ 

[1] ,Universidade do Porto Faculdade de Farmácia Serviço de Tecnologia FarmacêuticaPorto,Portugal

关键词: molecularly imprinted polymers (MIPs);    imprinting approaches;    MIPs characterization;   

DOI  :  10.1590/S0100-40422009000600045

来源: SciELO

【 摘 要 】

Molecularly imprinted polymers (MIPs) consist of synthetic macromolecular matrix, obtained through molecular imprinting-based methods that show ability to selectively recognize important biological molecules and its application in the drug delivery field is under development. In the present review the main aspects related to the synthesis and characterization of MIPs are studied. The fundamental variables participating in the synthesis process, such as template molecule, functional monomers, cross-linking agents, solvents and imprinting approaches are discussed. Moreover, the main available methods for MIPs chemical and morphological characterization are presented and the importance of the obtained information is discussed.

【 授权许可】

CC BY-NC   
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