Aplicação e avanços da espectroscopia de luminescência em análises farmacêuticas

Química Nova

Maria D. P. T. Sotomayor²  Iara Lúcia T. Dias¹  Marcos R. V. Lanza¹  Altair B. Moreira¹  Lauro T. Kubota¹ 

[1] ,Universidade Estadual Paulista Instituto de Química Departamento de Química AnalíticaAraraquara SP ,Brasil

关键词: luminescence spectroscopy;    drugs;    cosmetics analysis;   

DOI  :  10.1590/S0100-40422008000700031

来源: SciELO

【 摘 要 】

This paper provides a review on the latest advances and applications of the luminescence spectroscopy for the development of pharmaceuticals analyses methods, basically based on the photo- and chemiluminescence. The different forms of the drugs determination on pharmaceuticals through the fluorescence and chemiluminescence are discussed. The analyses include the drugs native fluorescence (liquid and solid-phases); the fluorescence from the oxidizing or reducing forms of the drug; the fluorescence from the chemical derivatization and their photochemistry and hydrolysis reactions. The quenching of luminescence and chemiluminescence generation for the pharmaceutical quantification are also shown. Finally, the trends and future perspectives of the luminescence spectroscopy in the field of the pharmaceutical research are discussed.

【 授权许可】

CC BY-NC   
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