Application and advances in the luminescence spectroscopy in pharmaceutical analyses

Química Nova

Kubota, Lauro T.¹  Sotomayor, Maria D. P. T.¹  Universidade Estadual Paulista, Araraquara, Brasil¹  Universidade São Francisco, Bragança Paulista, Brasil¹  Universidade Estadual Paulista, São José do Rio Preto, Brasil¹  Moreira, Altair B.¹  Universidade Estadual de Campinas, Campinas, Brasil¹  Lanza, Marcos R. V.¹  Dias, Iara Lúcia T.¹ 

关键词: luminescence spectroscopy;    drugs;    cosmetics analysis;   

DOI  :  10.1590/S0100-40422008000700031

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

This paper provides a review on the latest advances and applications of the luminescence spectroscopy for the development of pharmaceuticals analyses methods, basically based on the photo- and chemiluminescence. The different forms of the drugs determination on pharmaceuticals through the fluorescence and chemiluminescence are discussed. The analyses include the drugs native fluorescence (liquid and solid-phases); the fluorescence from the oxidizing or reducing forms of the drug; the fluorescence from the chemical derivatization and their photochemistry and hydrolysis reactions. The quenching of luminescence and chemiluminescence generation for the pharmaceutical quantification are also shown. Finally, the trends and future perspectives of the luminescence spectroscopy in the field of the pharmaceutical research are discussed.

【 授权许可】

Unknown