Influência do sulfato de condroitina na formação de filmes isolados de polimetacrilato: avaliação do índice de intumescimento e permeabilidade ao vapor d'água

Química Nova

Élcio José Bunhak²  Elisabete Scolin Mendes¹  Nehemias Curvelo Pereira¹  Osvaldo Albuquerque Cavalcanti¹ 

[1] ,Universidade Estadual do Oeste do ParanáCascavel PR ,Brasil

关键词: polymeric association;    chondroitin sulfate;    permeability;   

DOI  :  10.1590/S0100-40422007000200014

来源: SciELO

【 摘 要 】

Natural or modified chondroitin sulfate was incorporated in to polymethacrylate to obtain isolated films. The addition of polysaccharide to synthetic polymers occurred at different rates. Isolated films were micro and macroscopically characterized and swelling index and water vapor transmission were determined. Results indicated changed transparency and flexibility, coupled to their dependence on increase in polysaccharide concentration. A similar occurrence was reported in the permeability to water vapor and swelling degree. Films composed of modified chondroitin sulfate, 90:10 concentration, showed hydration levels, permeability and morphological properties which allow them to be applied as excipients in the development of new drug delivery systems.

【 授权许可】

CC BY-NC   
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