Kinetics of chronic inflammation in Nile tilapia fed n‑3 and n‑6 essential fatty acids

Pesquisa Agropecuária Brasileira

Róberson Sakabe¹  Flávio Ruas De Moraes¹  Marco Antonio De Andrade Belo¹  Fabiana Pilarski¹  Julieta Rodini Engrácia De Moraes¹ 

[1],Universidade Estadual Paulista Centro de Aquacultura Departamento de Patologia VeterináriaJaboticabal SP ,Brazil

关键词: Oreochromis niloticus;    foreign body;    growth performance;    inflammatory response;    lipid nutrition;    Oreochromis niloticus;    corpo estranho;    desempenho produtivo;    resposta inflamatória;    nutrição lipídica;   

DOI  :  10.1590/S0100-204X2013000300010

来源: SciELO

【 摘 要 】

The objective of this work was to investigate the effect of dietary supplementation with essential fatty acids on the kinetics of macrophage accumulation and giant cell formation in Nile tilapia (Oreochromis niloticus). The supplementation sources were soybean oil (SO, source of omega 6, n‑6) and linseed oil (LO, source of omega 3, n‑3), in the following proportions: 100% SO; 75% SO + 25% LO; 50% SO + 50% LO; 25% SO + 75% LO; and 100% LO (four replicates per treatment). After a feeding period of three months, growth performance was evaluated, and glass coverslips were implanted into the subcutaneous connective tissue of fish, being removed for examination at 2, 4, 6, and 8 days after implantation. Growth performance did not differ between treatments. Fish fed 100% linseed oil diet had the greatest macrophage accumulation and the fastest Langhans cell formation on the sixth day. On the eighth day, Langhans cells were predominant on the coverslips implanted in the fish feed 75 and 100% linseed oil. n‑3 fatty acids may contribute to macrophage recruitment and giant cell formation in fish chronic inflammatory response to foreign body.

【 授权许可】

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