Memórias do Instituto Oswaldo Cruz | |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil | |
Camila Marx1  Tatiana Schaffer Gregianini1  Fernanda Kieling Moreira Lehmann1  Vagner Ricardo Lunge1  Silvia De Carli1  Bibiana Paula Dambros1  Gabriela Luchiari Tumioto1  Claudete Seadi1  Andre Salvador Kazantzi Fonseca1  Nilo Ikuta1  | |
关键词: influenza A(H1N1)pmd09; resistance; oseltamivir; | |
DOI : 10.1590/S0074-02762013000300021 | |
来源: SciELO | |
【 摘 要 】
The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202005130048396ZK.pdf | 235KB | download |