Clinical-epidemiologic profile of the schistosomal myeloradiculopathy in Pernambuco, Brazil

Memórias do Instituto Oswaldo Cruz

Karina Conceição Gm De Araújo²  Cristiana Da Rosa E Silva²  Alexsandra Glória A Dos Santos²  Constança Simões Barbosa²  Teresa Ca Ferrari¹ 

[1] ,Centro de Pesquisas Aggeu Magalhães-Fiocruz Laboratório de Esquistossomose Recife PE ,Brasil

关键词: epidemiology;    schistosomiasis;    schistosomal myeloradiculopathy;    neuroschistosomiasis;    Schistosoma mansoni;   

DOI  :  10.1590/S0074-02762010000400017

来源: SciELO

【 摘 要 】

This was a retrospective descriptive study on a series of cases of schistosomal myeloradiculopathy (SMR) and the aim was to investigate the incidence of this disease and its clinical and epidemiological characteristics in cases diagnosed at three healthcare units in Pernambuco, Brazil between 1994-2006. The data were collected by reviewing the medical records from both the neurological and paediatric outpatient clinics and wards of the Hospital Clinics, Hospital of the Restoration and Pernambuco Mother and Child Institute. To gather the data, a spinal cord schistosomiasis evaluation protocol was used. The diagnoses were based on positive epidemiological evidence of schistosomiasis, clinical findings and laboratory tests (stool parasitological examination or rectal biopsies, magnetic resonance imaging findings and cerebrospinal fluid investigations). A total of 139 cases aged between 2-83 years were found. The most important determinants of SMR were male sex (66.2%), contact with fresh water (91%), origin in endemic regions (39.5%), lower-limb muscle weakness (100%), sensory level at the lower thoracic medulla (40.3%), myeloradicular form (76%) and presence of eggs in the stool parasitological examination (48%). This sample indicates the need for intervention policies guided by diagnostic standardization, thereby avoiding disease under-notification.

【 授权许可】

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