期刊论文详细信息
Memórias do Instituto Oswaldo Cruz
Helicobacter pylori detection in gastric biopsies, saliva and dental plaque of Brazilian dyspeptic patients
Lucas Trevizani Rasmussen2  Roger William De Labio1  Luciano Lobo Gatti1  Luiz Carlos Da Silva1  Valdeir Fagundes De Queiroz1  Marília De Arruda Cardoso Smith1  Spencer Luiz Marques Payão2 
[1] ,Universidade do Sagrado CoraçãoBauru SP ,Brasil
关键词: Helicobacter pylori;    oral infection;    saliva;    dental plaque;   
DOI  :  10.1590/S0074-02762010000300015
来源: SciELO
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【 摘 要 】

Helicobacter pylori is an important human pathogen that causes chronic gastritis and is associated with the development of peptic ulcer disease and gastric malignancies. The oral cavity has been implicated as a potential H. pylori reservoir and may therefore be involved in the reinfection of the stomach, which can sometimes occur following treatment of an H. pylori infection. The objectives of this paper were (i) to determine the presence of H. pylori in the oral cavity and (ii) to examine the relationship between oral H. pylori and subsequent gastritis. Gastric biopsies, saliva samples and dental plaques were obtained from 78 dyspeptic adults. DNA was extracted and evaluated for the presence of H. pylori using polymerase chain reaction and Southern blotting methods. Persons with gastritis were frequently positive for H. pylori in their stomachs (p < 0.0001) and there was a statistically significant correlation between the presence of H. pylori in gastric biopsies and the oral cavity (p < 0.0001). Our results suggest a relationship between gastric infection and the presence of this bacterium in the oral cavity. Despite this, H. pylori were present in the oral cavity with variable distribution between saliva and dental plaques, suggesting the existence of a reservoir for the species and a potential association with gastric reinfection.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License

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