Candida colonization in intensive care unit patients' urine

Memórias do Instituto Oswaldo Cruz

Xisto Sena Passos²  Werther Souza Sales¹  Patrícia Jackeline Maciel¹  Carolina Rodrigues Costa¹  Karla Carvalho Miranda¹  Janine De Aquino Lemos¹  Miranildes De Abreu Batista¹  Maria Do Rosário Rodrigues Silva¹ 

[1] ,Universidade PaulistaGoiânia GO ,Brasil

关键词: nosocomial infections;    predisposing factors;    intensive care unit;    Candida spp.;    Brazil;   

DOI  :  10.1590/S0074-02762005000800016

来源: SciELO

【 摘 要 】

The objective of this study was to identify possible predisposing factors for candiduria in intensive care unit (ICU) patients from Hospital das Clínicas, Universidade Federal de Goiás, Goiânia, Brazil, during one year. Urine samples from 153 ICU patients were obtained by catheterization on admission day and every seven days. Data such as sex, age, antifungal therapy, and variables as antibiotics, underlying diseases or comorbid conditions and stay in the hospital, were collected from patients who had at least one urine culture that yielded > 10³ yeast colonies/ml. Candiduria was recovered in 68 patients and the commonest predisposing factors were antibiotic therapy (100%) and indwelling urinary catheter (92.6%). The percentage of Candida spp. isolation increased during the extended periods in which patients remained in the ICU. C. albicans was isolated in 69.1%, and the other species non-albicans as C. glabrata, C. kefyr, C. parapsilosis, C. famata, C. guilliermondii, C. krusei, and C. tropicalis were isolated in lower percentage. The high frequency of candiduria and the possible predisposing factors found in ICU patients show that candiduria surveillance should be performed to help reducing nosocomial infections.

【 授权许可】

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