Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit

Racionalna Terapija

Đorđević Zorana M.¹  Radojević-Živković Marija N.²  Janković Slobodan M.³  Protrka Zoran M.⁴  Savić Dragana M.⁵  Ristić Dragana⁵  Rajković Gordana⁵  Opančina Valentina D.⁶ 

[1] Klinika za epidemiologiju, Klinički centar, Kragujevac;Klinički centar Kragujevac, Klinika za onkologiju;Univerzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za farmakologiju i toksikologiju;Univerzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za ginekologiju i akušerstvo;Univerzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za pedijatriju + Klinički centar Kragujevac, Klinika za pedijatriju;Univerzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za radiologiju;

关键词: nosocomial infections;    mechanic ventilation;    neonates;    intensive care unit;   

DOI  :  

来源: DOAJ

【 摘 要 】

Introduction. Neonatal nosocomial infection (NIs) is defined as the occurrence of infection 48 hours after birth, which is caused by a nosocomial pathogen. Newborns admitted to neonatal intensive care units (NICU) are at increased risk for developing Nis. The aim of our study was to describe risk factors for NIs at mechanically ventilated (MV) neonates in a NICU. Materials and methods. The study was designed as a case/control study nested in the prospective cohort study. The study population consisted of the neonates supported by MV and admitted at the NICU. Risk factors were identified and their influence quantified by logistic regression. Results. Our study showed that MV neonates in the NICU, who were longer carrying peripheral venous catheter (PVC) and spend more time in hospital, were more likely to get NIs (OR=1.091, CI=1.035-1.151). The neonates having an infection on admittance were less likely to acquire NIs. Conclusions. Development of NIs in MV neonates could be prevented by education of hospital staff and shortening of hospitalization. Rate of nosocomial infections will drop if exposure of newborns to pathogens from hospital environment and to invasive devices is decreased.

【 授权许可】

Unknown