Analysis of the clonal diversity of Staphylococcus aureus methicillin-resistant strains isolated at João Pessoa, state of Paraíba, Brazil

Memórias do Instituto Oswaldo Cruz

Lauro Santos Filho²  Helio Silva Sader¹  Vania I Bortolotto¹  Paulo P Gontijo Filho¹  Antonio C Pignatari¹ 

[1] ,UFPb Departamento de Ciências Farmacêuticas João Pessoa PB ,Brasil

关键词: Staphylococcus aureus;    molecular epidemiology;    antimicrobial resistance;   

DOI  :  10.1590/S0074-02761996000100018

来源: SciELO

【 摘 要 】

To investigate the clonal diversity of Staphylococcus aureus strains isolated at João Pessoa, State of Paraíba, Brazil, digested genomic DNA were studied by pulsed-field gel electrophoresis (PFGE) in nine methicillin-resistant strains (MRSA) and three methicillin-sensitive strains (MSSA), selected among 67 isolates based on their antimicrobial susceptibility and epidemiology. The isolates were obtained between April and November 1992 from the Hospital of the Federal University of Paraíba, located in João Pessoa. Two MRSA isolates from the Oswaldo Cruz Hospital, São Paulo, Brazil, including an epidemic strain previously detected from different hospitals at the country were used as control. Five different patterns, were demonstrated by MRSA isolated in João Pessoa and these patterns were described in several epidemiologically unrelated hospitals in São Paulo. Our results suggest the interstate dissemination of a MRSA clone in João Pessoa which is similar to that described in other cities of Brazil.

【 授权许可】

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