A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis

Memórias do Instituto Oswaldo Cruz

Luis Valda Rodriguez²  Jean-pierre Dedet¹  Virginia Paredtes²  Carmelo Mendoza²  Fernando Cardenas² 

[1] ,Hospital de Clinicas Universitario Servicio de Dermatologia Miraflores,Bolivia

关键词: mucocutaneous leishmaniasis;    treatmetn;    amphotericin B;    itraconazole;   

DOI  :  10.1590/S0074-02761995000400020

来源: SciELO

【 摘 要 】

A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.

【 授权许可】

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