Recent advances and prospective researches on molecular epidemiology of dengue viruses

Memórias do Instituto Oswaldo Cruz

Vincent Deubel¹ 

[1] ,Institut Pasteur Laboratory of Arboviruses Paris,France

关键词: dengue virus;    molecular epidemiology;    sequencing;    envelope protein;   

DOI  :  10.1590/S0074-02761992000900021

来源: SciELO

【 摘 要 】

The determination of amino acid changes in the envelop protein by direct sequencing of either genomic RNA or PCR-amplified cDNA fragments provides useful informations for assessing the genetic variability and the geographic distribution of the actually most widespread dengue-2 serotype. The possible link of variations in the envelope protein-gene and virus virulence is discussed.

【 授权许可】

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